What are the latest liver-protective ingredients? Is PQQ+ in

A nutritionist once stated that if you could choose only one nutritional supplement, it should definitely be a liver-protective tablet.

The liver is often likened to the most crucial chemical factory in the human body, playing a vital role in the metabolism of sugar, fat, proteins, and the conversion of most toxic substances. Virtually every physiological function is dependent on the liver.

However, with the accelerated pace of modern life, socializing, staying up late, and overtime work have become commonplace, putting a significant burden on the liver. Irregular eating habits, imbalanced nutrition, prolonged intake of high-fat and high-sugar foods, lack of exercise, and the age-related decline in liver cell function contribute to the increasing prevalence of fatty liver disease, affecting people at a younger age.

In a 2019 report on 'Health Big Data,' it was explicitly stated that 76% of white-collar workers are in a sub-healthy state, and approximately 120 million people suffer from liver-related diseases. The incidence of liver diseases is on the rise, necessitating a heightened awareness of liver protection. Apart from avoiding staying up late, maintaining a regular sleep schedule, and refraining from smoking and drinking, liver protection has become a focus of public attention.

Liver-protective ingredients can be broadly categorized into three types: herbal, milk thistle, and cellular coenzyme.

1. herbal liver protection

It is a relatively traditional approach. Mainstream ingredients include curcumin, kudzu root powder, pig liver and gallbladder powder, Artemisia capillaris, Schisandra chinensis, etc. These herbal components work by promoting liver fat metabolism, reducing cholesterol, and decreasing the accumulation of triglycerides in the liver to protect it.

However, herbal liver protection has significant drawbacks. Individual differences play a significant role, and the effects vary from person to person. Some individuals may experience allergic reactions to specific herbal components. Long-term or excessive consumption of herbal ingredients may cause gastrointestinal discomfort, diarrhea, indigestion, and even allergic reactions such as itching and difficulty breathing. Therefore, herbal liver protection requires careful consideration.

2. Milk Thistle

It is also known as "Silybum marianum" or "water thistle," is a potent antioxidant with positive effects on liver diseases such as hepatitis, cirrhosis, and damage caused by drugs and alcohol. It is particularly effective in stimulating protein synthesis, accelerating metabolism, and reducing the burden on the liver.

However, milk thistle may have limitations, such as poor suitability for individuals allergic to it, also it has the potential to cause diarrhea in individuals with a weak intestinal environment; and its weak estrogenic effect may not be suitable for most women. Additionally, as a plant-based ingredient, milk thistle may face challenges in providing deep-level maintenance for the liver.

Apart from these two types, a new category of liver-protective ingredients has recently gained popularity. Are these ingredients really effective? Are they safe?

3. Cellular Coenzyme Ingredients 

It has gained attention in recent years within academic circles. Their advantage lies in being a collective term for a large category of organic auxiliary factors in the human body.

Research has confirmed that coenzymes can activate cellular nutrition and energy, enhance immunity, strengthen antioxidant capabilities, slow down aging, boost vitality, and protect the liver.

Since most biochemical reactions occur in the liver, it naturally requires more coenzymes for energy metabolism and conversion. However, as age increases, the body's ability to self-synthesize coenzymes gradually declines. External supplementation of coenzymes becomes necessary, and oral coenzyme supplements are a direct way to protect liver cells.

Cellular-level liver protection coenzymes mainly include PQQ and inositol.

PQQ has attracted significant attention in academic circles since its discovery. It has been approved by the United States Food and Drug Administration (FDA) GRAS and the Chinese National Health Commission，which has obtained exclusive patents for improving alcoholic fatty liver (ZL 02111549.4).

PQQ has been proven to directly impact liver cells, increase the number of fresh mitochondria in liver cells, effectively enhancing the liver's metabolic capacity. This is akin to adding many "small engines" to the liver, helping it metabolize excess fat, waste, and toxins, reducing damage caused by fat to the liver.

Additionally, PQQ's potent antioxidant properties can eliminate excess free radicals in cells, reducing their harm.

Compared to silymarin (the main component of milk thistle), PQQ has demonstrated good performance in resisting the further development of liver damage, reducing liver inflammation and fibrosis. It is particularly suitable for individuals with fatty liver.

Inositol is a natural water-soluble vitamin belonging to the B family of vitamins. Its key function is to emulsify fats, earning it the nickname "anti-fatty liver vitamin." Therefore, inositol is especially suitable for individuals with fatty liver. By speeding up the metabolic regulation process of body fat, inositol can emulsify and eliminate excess fat from the liver, reducing the likelihood of fatty liver. It can also help suppress the increase in cholesterol levels caused by alcohol, particularly effective in alcoholic fatty liver.

Cholesterol is a significant component of blood lipids, along with triglycerides, they contribute to elevated blood lipid levels together. Inositol can effectively lower serum cholesterol levels, and research indicates that as inositol content increases within a certain range, the effect of lowering cholesterol becomes more pronounced.

These two major ingredients are emerging as effective options for liver protection.

The above passage discusses the two main components that are also the result of years of research by the ESTHELIV R&D team. The team has obtained patents related to liver protection based on these components. Inspired by these patents, they have introduced a liver protection product called Liver Detox Capsules targeting fatty liver, aiming to rejuvenate a "liver-clean life."

In comparison to the single component milk thistle, ESTHELIV utilizes high-purity, high-stability, and uniquely crystalline PQQ raw material combined with emulsified fat-soluble inositol. These two components work together on the liver, not only enhancing liver cell function, reducing free radical damage, and preventing fatty liver but also improving energy levels through enhanced metabolic capacity. This contributes to uplifting one's spirits, achieving the dual purpose of liver protection and nourishment.